5 facts about Viagra that you probably do not know

Generic Viagra appeared in December 2017 and its price is 2 times lower than that of the well-known analog.

5 facts about Viagra that you probably do not know



Pfizer, which makes Viagra, will produce its own generic drug, containing the active ingredient sildenafil. 

It is white, not blue, and costs 2 times cheaper than Viagra. By selling its own universal version, Pfizer will be able to compete with other pharmaceutical companies.


Here are five interesting facts about Viagra (sildenafil):

1) Initially, Viagra was intended for the treatment of chest pain.

When the researchers first created sildenafil in the 1980s, it was designed to treat angina pectoris or chest pain caused by a decrease in blood flow to the heart, according to a 2004 review article.

However, in an early study, the drug did not produce cardiac effects, which the researchers hoped for. But a number of volunteer researchers reported an interesting side effect – they had stronger and more persistent erections.

2) The drug works by blocking the enzyme in the tissues of the penis.

At the molecular level, sildenafil inhibits an enzyme called phosphodiesterase 5 (PDE5), and does not allow this enzyme to work too fast. 

PDE5 occurs in a variety of tissues, including the penis. 

The enzyme plays a role in regulating blood flow to the penis, and by blocking the enzyme, and the overall effect of sildenafil is to increase the flow of blood to the penis, which leads to an erection.

3) Viagra does not stimulate sex drive.

Some men are reported to take drugs for recreational purposes, believing that this will contribute to their sexual attraction. 

But sildenafil does not increase sexual desire. 

According to Pfizer, the drug will not cause an erection itself – it works only when a man is sexually stimulated.

4) Viagra should not be taken with certain medicines.

Not all men with erectile dysfunction can take sildenafil. According to Pfizer, those who take certain medications should not take a cure for erectile dysfunction because of the risk of serious side effects. 

For example, drugs called nitrates, which are often prescribed for joint pain, and drugs called guanylate cyclase stimulants that are prescribed for pulmonary hypertension (high blood pressure type), can lead to an unsafe decrease in blood pressure if taken in conjunction with sildenafil, according to Pfizer.

5) Erectile dysfunction is not the only thing that sildenafil treats.

Sildenafil is also approved for the treatment of pulmonary arterial hypertension, high blood pressure in vessels that carry blood to the lungs. 

The drug treats this condition by relaxing the blood vessels in the lungs, which allows blood to flow more easily. Sildenafil is even used to help premature babies with this condition. 

When used for this condition, sildenafil is sold under the trademark Revatio (also manufactured by Pfizer

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